A plugin for ICM+® that allows to calculate non-invasive ICP from TCD, FV, and ABP signals.

A PROCEDURE OF NON-INVASIVE ASSESSMENT OF INTRACRANIAL PRESSURE

Development: Bernhard Schmidt, Juergen Klingelhoefer, Marek Czosnyka.
Software Realization and Integration: Bernhard Schmidt, Ronny Plontke, Peter Smielewski.
*Protected by Patent: DE 19600983

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How it works:

 

From measured FV and ABP signals, sets of parameters called TCD characteristics are computed. Using our specific procedure algorithm from the TCD characteristics, the impulse response function is generated. The impulse response function transforms the ABP signal into the target signal, the nICP signal. (FV: blood Flow Velocity assessed by TCD in the middle cerebral artery;  TCD: Transcranial Doppler ultrasonography; ABP: Arterial Blood Pressure; nICP: non-invasive Intracranial Pressure). View image

References:

  1. Schmidt B, Klingelhöfer J, Schwarze JJ, Sander D, Wittich I (1997) Noninvasive prediction of intracranial pressure curves using transcranial Doppler ultrasonography and blood pressure curves. Stroke 28:2465-2472
  2. Schmidt B, Schwarze JJ, Czosnyka M, Sander D, Wittich I, Klingelhöfer J (1998) A method for a simulation of continuous intracranial pressure curves. Comp Biomed Res 31(4):231-243
  3. Schmidt B, Czosnyka M, Schwarze JJ, Sander D, Gerstner W, Lumenta CB, Pickard JD, Klingelhöfer J (1999) Cerebral vasodilatation causing acute intracranial hypertension- a method for non-invasive assessment. J Cereb Blood Flow Metab 19:990-996
  4. Schmidt B, Czosnyka M, Schwarze JJ, Sander D, Gerstner W, Lumenta CB, Klingelhöfer J (2000) Evaluation of a method for noninvasive intracranial pressure assessment during infusion studies in patients with hydrocephalus. J Neurosurg 92:793-800
  5. Schmidt B, Czosnyka M, Raabe A, Yahya H, Schwarze JJ, Sackerer D, Sander D, Klingelhöfer J (2003) Adaptive non-invasive assessment of cerebral autoregulation and ICP. Stroke 34:84-89 Schmidt B, Czosnyka M, Schwarze JJ, Sander D, Gerstner W, Lumenta CB, Klingelhöfer J (2000) Evaluation of a method for noninvasive intracranial pressure assessment during infusion studies in patients with hydrocephalus. J Neurosurg 92:793-800
  6. Schmidt B, Czosnyka M, Raabe A, Yahya H, Schwarze JJ, Sackerer D, Sander D, Klingelhöfer J (2003) Adaptive non-invasive assessment of cerebral autoregulation and ICP. Stroke 34:84-89

 

For more information on please contact: bschmidt99@gmx.de